ABSTRACT The high global burden of cryptococcosis has made development of a protective vaccine a public health priority.We previously demonstrated that a vaccine composed of recombinant Cryptococcus neoformans chitin deacetylase 2 (Cda2) delivered in glucan particles (GPs) protects BALB/c and C57BL/6 mice from an otherwise lethal challenge with a h

Cancer metastasis is a major cause of mortality from several tumors, including those of the breast, prostate, and the thyroid gland.Since bone tissue is one of the most common sites of metastasis, the treatment of bone metastases is crucial for the cure of cancer.Hence, disease hellcat spark plugs models must be developed to understand the process

glass.dildo BACKGROUND: Sequence analysis is a set of tools increasingly used in demography and other social sciences to analyse longitudinal categorical data.Typically, single (e.g., education trajectories) or multiple parallel temporal processes (e.g., work and family) are analysed by using crisp clustering algorithms that reduce complexity by pa